Chrm4 | cholinergic receptor, muscarinic 4

GeneMGI:88399Synonyms: muscarinic acetylcholine receptor 4, Chrm-4

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Behavior/neurological

16 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes



hyperactivity	5 supporting datasets	Chrm4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.37x10^-6
increased startle reflex	1 supporting dataset	Chrm4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.52x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Chrm4.

Associated images

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Histopathology

There is no histopathology data found for Chrm4.

IMPC related publications

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External links

No external links available for Chrm4.

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*Chrm4^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Chrm4^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Chrm4^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Chrm4^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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