Cd27 | CD27 antigen

GeneMGI:88326Synonyms: Tnfrsf7, Tp55, +2 more

Physiological systems

22 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Limbs/digits/tail Nervous system Hematopoietic system Cardiovascular system

14 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal testis morphology	1 supporting dataset	Cd27^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Cd27^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Cd27^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased lean body mass	1 supporting dataset	Cd27^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.31x10^-5
abnormal heart morphology	1 supporting dataset	Cd27^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number	1 supporting dataset	Cd27^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.47x10^-5
small testis	1 supporting dataset	Cd27^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal digit morphology	1 supporting dataset	Cd27^{em1(IMPC)Ccpcz}	homozygote	Early adult	7.12x10^-5
increased prepulse inhibition	1 supporting dataset	Cd27^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.68x10^-5
small seminal vesicle	1 supporting dataset	Cd27^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cd27.

Associated images

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Histopathology

There is no histopathology data found for Cd27.

IMPC related publications

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External links

No external links available for Cd27.

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*Cd27^{em1(IMPC)Ccpcz}*	Intra-exon deletion	‌	mouse
*Cd27^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Cd27^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Cd27^{tm379101(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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