C4bp | complement component 4 binding protein

Physiological systems

20 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Homeostasis/metabolism

19 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating HDL cholesterol level1 supporting datasetC4bptm1b(KOMP)WtsihomozygoteEarly adult8.6x10-5 
increased circulating cholesterol level1 supporting datasetC4bptm1b(KOMP)WtsihomozygoteEarly adult1.11x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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C4bptm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
C4bptm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
C4bptm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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