C1qc | complement component 1, q subcomponent, C chain

GeneMGI:88225Synonyms: C1qg

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Limbs/digits/tail Behavior/neurological

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased grip strength1 supporting datasetC1qcem1(IMPC)JhomozygoteEarly adult2.13x10-5 
increased circulating total protein level1 supporting datasetC1qcem1(IMPC)JhomozygoteLate adult4.07x10-5 
abnormal startle reflex1 supporting datasetC1qcem1(IMPC)JhomozygoteLate adult1.94x10-6 
increased circulating alanine transaminase level1 supporting datasetC1qcem1(IMPC)JhomozygoteLate adult1.51x10-6 
abnormal autopod morphology1 supporting datasetC1qcem1(IMPC)JhomozygoteLate adult2.23x10-8 
absent vibrissae1 supporting datasetC1qcem1(IMPC)JhomozygoteLate adult1.85x10-5 
increased circulating calcium level1 supporting datasetC1qcem1(IMPC)JhomozygoteLate adult7.06x10-6 
increased circulating aspartate transaminase level1 supporting datasetC1qcem1(IMPC)JhomozygoteLate adult2.19x10-14 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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C1qcem1(IMPC)JExon Deletionmouse

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