Atp2a2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
Physiological systems
18 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system Mortality/aging
15 No significant impact
6 Not tested
Data collections
Gene metrics:4Significant phenotypes
4Associated diseases
Expression examined in:46Adult tissues
21Embryo tissues
decreased circulating alkaline phosphatase level | 1 supporting dataset | Atp2a2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 2.81x10-5 | ||
preweaning lethality, complete penetrance | 1 supporting dataset | Atp2a2tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
increased fasting circulating glucose level | 1 supporting dataset | Atp2a2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 6.23x10-5 | ||
decreased mean platelet volume | 1 supporting dataset | Atp2a2tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 9.2x10-12 |
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External links
No external links available for Atp2a2.
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Atp2a2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
Atp2a2tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Atp2a2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |