Aprt | adenine phosphoribosyl transferase

GeneMGI:88061

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal retina morphology	1 supporting dataset	Aprt^{em1(IMPC)Hmgu}	homozygote	Early adult	9.53x10^-7
preweaning lethality, incomplete penetrance	1 supporting dataset	Aprt^{em1(IMPC)Hmgu}	homozygote	Early adult	N/A ^*
increased respiratory quotient	1 supporting dataset	Aprt^{em1(IMPC)Hmgu}	heterozygote	Early adult	4.94x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Aprt.

Associated images

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Histopathology

There is no histopathology data found for Aprt.

IMPC related publications

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External links

No external links available for Aprt.

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*Aprt^{em1(IMPC)Hmgu}*	Exon Deletion	‌	mouse
*Aprt^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell

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