Aplp2 | amyloid beta precursor-like protein 2

GeneMGI:88047

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Limbs/digits/tail Hematopoietic system Skeleton

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



short tibia	1 supporting dataset	Aplp2^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	9.63x10^-5
decreased bone mineral density	1 supporting dataset	Aplp2^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	3.71x10^-6
decreased mean corpuscular volume	1 supporting dataset	Aplp2^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	3.38x10^-10

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Aplp2.

Associated images

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Histopathology

There is no histopathology data found for Aplp2.

IMPC related publications

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External links

No external links available for Aplp2.

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*Aplp2^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Aplp2^{tm2b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Aplp2^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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