Aldoa | aldolase A, fructose-bisphosphate

GeneMGI:87994Synonyms: Aldo1, Aldo-1

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Vision/eye Hematopoietic system Behavior/neurological Mortality/aging

15 No significant impact

4 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:51Adult tissues
62Embryo tissues

Phenotypes

decreased leukocyte cell number1 supporting datasetAldoatm1.1(KOMP)WtsiheterozygoteEarly adult1.84x10-8 
preweaning lethality, complete penetrance3 supporting datasetsAldoatm1.1(KOMP)WtsihomozygoteEarly adultN/A * 
decreased thigmotaxis1 supporting datasetAldoatm1.1(KOMP)WtsiheterozygoteEarly adult2.72x10-5 
decreased total retina thickness1 supporting datasetAldoatm1.1(KOMP)WtsiheterozygoteEarly adult3.3x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Aldoatm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Aldoatm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
mouse
Aldoatm1.1(KOMP)WtsiReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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