Adss2 | adenylosuccinate synthase 2

GeneMGI:87948Synonyms: AS, Adss

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Mortality/aging

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

21Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased blood urea nitrogen level	1 supporting dataset	Adss2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	3.68x10^-6
embryonic lethality prior to tooth bud stage	1 supporting dataset	Adss2^{tm1b(EUCOMM)Wtsi}	homozygote	E12.5	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Adss2^{tm1b(EUCOMM)Wtsi}	homozygote	E9.5	N/A ^*
increased circulating HDL cholesterol level	1 supporting dataset	Adss2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	5.85x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Adss2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased circulating creatinine level	1 supporting dataset	Adss2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	4.38x10^-6
decreased eosinophil cell number	1 supporting dataset	Adss2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	6.61x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Adss2.

Associated images

Loading...

Histopathology

There is no histopathology data found for Adss2.

IMPC related publications

Loading...

External links

No external links available for Adss2.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Adss2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Adss2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Adss2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Adss2^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Adss2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Adss2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes