Acy1 | aminoacylase 1

GeneMGI:87913Synonyms: 1110014J22Rik, Acy-1

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument Behavior/neurological Cardiovascular system

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal coat/hair pigmentation	2 supporting datasets	Acy1^em1(IMPC)J	homozygote	Late adult	1.29x10^-7
decreased grip strength	2 supporting datasets	Acy1^em1(IMPC)J	homozygote	Late adult	6.37x10^-6
abnormal sinus arrhythmia	1 supporting dataset	Acy1^em1(IMPC)J	homozygote	Late adult	3.55x10^-5
abnormal startle reflex	1 supporting dataset	Acy1^em1(IMPC)J	homozygote	Late adult	8.97x10^-5
abnormal gait	1 supporting dataset	Acy1^em1(IMPC)J	homozygote	Late adult	7.96x10^-9
increased circulating bilirubin level	1 supporting dataset	Acy1^em1(IMPC)J	homozygote	Early adult	6.77x10^-5
abnormal coat/ hair morphology	1 supporting dataset	Acy1^em1(IMPC)J	homozygote	Late adult	3.14x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Acy1.

Associated images

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Histopathology

There is no histopathology data found for Acy1.

IMPC related publications

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External links

No external links available for Acy1.

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*Acy1^em1(IMPC)J*	Exon Deletion	‌	mouse
*Acy1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Acy1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Acy1^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Acy1^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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