Chrnd | cholinergic receptor, nicotinic, delta polypeptide

GeneMGI:87893Synonyms: Achr-4, Acrd

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Integument Embryo Growth/size/body region Vision/eye Mortality/aging Renal/urinary system

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

6Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal placenta morphology	1 supporting dataset	Chrnd^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
small kidney	1 supporting dataset	Chrnd^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal retina morphology	1 supporting dataset	Chrnd^em1(IMPC)Mbp	heterozygote	Early adult	2.94x10^-5
abnormal skin morphology	1 supporting dataset	Chrnd^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
embryonic growth retardation	1 supporting dataset	Chrnd^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Chrnd^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Chrnd^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal vitreous body morphology	1 supporting dataset	Chrnd^em1(IMPC)Mbp	heterozygote	Early adult	9.49x10^-7
microphthalmia	1 supporting dataset	Chrnd^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Chrnd.

Associated images

Loading...

Histopathology

There is no histopathology data found for Chrnd.

IMPC related publications

Loading...

External links

No external links available for Chrnd.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Chrnd^em1(IMPC)Mbp*	Inter-exon deletion	‌	mouse
*Chrnd^em1H*	Point Mutation	‌	mouse
*Chrnd^{tm1(EGFP_CreERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Chrnd^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Chrnd^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes