Apoc4 | apolipoprotein C-IV

GeneMGI:87878Synonyms: Acl

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Vision/eye Hematopoietic system Behavior/neurological

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating triglyceride level	1 supporting dataset	Apoc4^{tm1.1(KOMP)Mbp}	homozygote	Early adult	9.91x10^-145
increased leukocyte cell number	1 supporting dataset	Apoc4^{tm1.1(KOMP)Mbp}	homozygote	Early adult	2.49x10^-6
decreased exploration in new environment	1 supporting dataset	Apoc4^{tm1.1(KOMP)Mbp}	homozygote	Early adult	9.6x10^-5
abnormal lens morphology	1 supporting dataset	Apoc4^{tm1.1(KOMP)Mbp}	homozygote	Early adult	4.39x10^-5
decreased circulating chloride level	1 supporting dataset	Apoc4^{tm1.1(KOMP)Mbp}	homozygote	Early adult	4.77x10^-6
decreased circulating cholesterol level	1 supporting dataset	Apoc4^{tm1.1(KOMP)Mbp}	homozygote	Early adult	1.17x10^-9
impaired glucose tolerance	2 supporting datasets	Apoc4^{tm1.1(KOMP)Mbp}	homozygote	Early adult	6.84x10^-6
increased circulating alanine transaminase level	1 supporting dataset	Apoc4^{tm1.1(KOMP)Mbp}	homozygote	Early adult	1.15x10^-9
increased circulating alkaline phosphatase level	1 supporting dataset	Apoc4^{tm1.1(KOMP)Mbp}	homozygote	Early adult	1.75x10^-8
decreased circulating HDL cholesterol level	1 supporting dataset	Apoc4^{tm1.1(KOMP)Mbp}	homozygote	Early adult	8.78x10^-24

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Apoc4.

Associated images

Loading...

Histopathology

There is no histopathology data found for Apoc4.

IMPC related publications

Loading...

External links

No external links available for Apoc4.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Apoc4^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell mouse
*Apoc4^{tm1.1(KOMP)Mbp}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Apoc4^{tm454848(L1L2_GT1_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes