Ace | angiotensin I converting enzyme
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Immune system Embryo Growth/size/body region Hematopoietic system Behavior/neurological Mortality/aging
13 No significant impact
5 Not tested
Gene metrics:5Significant phenotypes
4Associated diseases
Expression examined in:73Adult tissues
29Embryo tissues
| increased basophil cell number | 1 supporting dataset | Acetm1.1(KOMP)Vlcg | heterozygote | Early adult | 4.32x10-6 | ||
| hyperactivity | 1 supporting dataset | Acetm1.1(KOMP)Vlcg | heterozygote | Early adult | 6.37x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Acetm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Acetm1.1(KOMP)Vlcg | heterozygote | E9.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Acetm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Acetm1.1(KOMP)Vlcg | heterozygote | E9.5 | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Acetm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * |
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External links
No external links available for Ace.
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| Acetm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Acetm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Acetm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |