Acat2 | acetyl-Coenzyme A acetyltransferase 2
Physiological systems
22 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Behavior/neurological Mortality/aging
17 No significant impact
2 Not tested
Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:49Adult tissues
62Embryo tissues
| unresponsive to tactile stimuli | 1 supporting dataset | Acat2tm1b(KOMP)Wtsi | homozygote | E18.5 | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Acat2tm1b(KOMP)Wtsi | homozygote | E18.5 | N/A * | ||
| unresponsive to tactile stimuli | 1 supporting dataset | Acat2tm1b(KOMP)Wtsi | heterozygote | E18.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Acat2tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| abnormal body wall morphology | 1 supporting dataset | Acat2tm1b(KOMP)Wtsi | homozygote | E18.5 | N/A * | ||
| increased circulating chloride level | 1 supporting dataset | Acat2tm1b(KOMP)Wtsi | heterozygote | Early adult | 7.81x10-7 | ||
| increased body length | 1 supporting dataset | Acat2tm1b(KOMP)Wtsi | heterozygote | Early adult | 6.2x10-5 |
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External links
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| Acat2tm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Acat2tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Acat2tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |