Mthfsl | 5, 10-methenyltetrahydrofolate synthetase-like
Physiological systems
18 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Vision/eye Behavior/neurological
16 No significant impact
6 Not tested
Data collections
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:70Adult tissues
0Embryo tissues
cataract | 1 supporting dataset | Mthfsltm1b(EUCOMM)Hmgu | homozygote | Early adult | 8.22x10-7 | ||
abnormal lens morphology | 1 supporting dataset | Mthfsltm1b(EUCOMM)Hmgu | homozygote | Early adult | 3.27x10-7 | ||
decreased grip strength | 1 supporting dataset | Mthfsltm1b(EUCOMM)Hmgu | homozygote | Early adult | 9.88x10-7 |
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External links
No external links available for Mthfsl.
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Mthfsltm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
Mthfsltm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Mthfsltm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |