Mthfsl | 5, 10-methenyltetrahydrofolate synthetase-like

GeneMGI:3780550Synonyms: Gm2382

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Behavior/neurological

16 No significant impact

6 Not tested

Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:70Adult tissues
0Embryo tissues

Phenotypes

cataract1 supporting datasetMthfsltm1b(EUCOMM)HmguhomozygoteEarly adult8.22x10-7 
abnormal lens morphology1 supporting datasetMthfsltm1b(EUCOMM)HmguhomozygoteEarly adult3.27x10-7 
decreased grip strength1 supporting datasetMthfsltm1b(EUCOMM)HmguhomozygoteEarly adult9.88x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  

lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mthfsltm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Mthfsltm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Mthfsltm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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