Tomt | transmembrane O-methyltransferase

GeneMGI:3769724Synonyms: Comt2, F930017I19Rik

Physiological systems

15 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Reproductive system Hearing/vestibular/ear Vision/eye Hematopoietic system Behavior/neurological

10 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:12Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal auditory brainstem response4 supporting datasetsTomtem1(IMPC)TcphomozygoteEarly adult1.61x10-6 
decreased thigmotaxis2 supporting datasetsTomtem1(IMPC)TcphomozygoteEarly adult1.58x10-6 
hyperactivity9 supporting datasetsTomtem1(IMPC)TcphomozygoteEarly adult8.64x10-88 
decreased anxiety-related response1 supporting datasetTomtem1(IMPC)TcphomozygoteEarly adult1.16x10-17 
abnormal uterus morphology1 supporting datasetTomtem1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal startle reflex1 supporting datasetTomtem1(IMPC)TcphomozygoteEarly adult3.71x10-9 
head bobbing1 supporting datasetTomtem1(IMPC)TcphomozygoteEarly adult3.44x10-21 
decreased exploration in new environment1 supporting datasetTomtem1(IMPC)TcphomozygoteEarly adult1.84x10-15 
increased mean platelet volume1 supporting datasetTomtem1(IMPC)TcphomozygoteEarly adult3.38x10-5 
abnormal behavior2 supporting datasetsTomtem1(IMPC)TcphomozygoteEarly adult1.58x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  
Rows per page: 










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Tomtem1(IMPC)TcpIntra-exon deletionmouse
Tomttm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter