Aktip | AKT interacting protein

GeneMGI:3693832Synonyms: Ft1

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Behavior/neurological Skeleton

13 No significant impact

7 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

hyperactivity4 supporting datasetsAktiptm1b(EUCOMM)HmguhomozygoteEarly adult2.95x10-9 
decreased bone mineral content2 supporting datasetsAktiptm1b(EUCOMM)HmguhomozygoteEarly adult1.15x10-8 
increased circulating aspartate transaminase level1 supporting datasetAktiptm1b(EUCOMM)HmguhomozygoteEarly adult4.38x10-5 
decreased bone mineral density1 supporting datasetAktiptm1b(EUCOMM)HmguhomozygoteEarly adult8.18x10-14 
abnormal retina morphology1 supporting datasetAktiptm1b(EUCOMM)HmguhomozygoteEarly adult2.46x10-5 
abnormal gait1 supporting datasetAktiptm1b(EUCOMM)HmguhomozygoteEarly adult9.33x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Aktiptm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Aktiptm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Aktiptm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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