Dact3 | dishevelled-binding antagonist of beta-catenin 3

GeneMGI:3654828Synonyms: EG666671

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region

16 No significant impact

6 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

improved glucose tolerance1 supporting datasetDact3tm1b(KOMP)WtsihomozygoteEarly adult2.24x10-7 
increased lean body mass1 supporting datasetDact3tm1b(KOMP)WtsihomozygoteEarly adult1.01x10-5 
decreased circulating serum albumin level1 supporting datasetDact3tm1b(KOMP)WtsihomozygoteEarly adult6.4x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dact3tm114992(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Dact3tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Dact3tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Dact3tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Dact3tm2e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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