Obp2b | odorant binding protein 2B

GeneMGI:3651927Synonyms: Lcn14, OTTMUSG00000012631

Physiological systems

19 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Cardiovascular system Mortality/aging Renal/urinary system

11 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

prolonged RR interval1 supporting datasetObp2bem1(IMPC)KmpchomozygoteLate adult2.23x10-6 
preweaning lethality, incomplete penetrance1 supporting datasetObp2bem1(IMPC)KmpchomozygoteEarly adultN/A * 
abnormal seminal vesicle morphology1 supporting datasetObp2bem1(IMPC)KmpchomozygoteLate adultN/A * 
enlarged kidney1 supporting datasetObp2bem1(IMPC)KmpchomozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetObp2bem1(IMPC)KmpchomozygoteEarly adultN/A * 
abnormal coat/ hair morphology1 supporting datasetObp2bem1(IMPC)KmpchomozygoteLate adult1.57x10-5 
abnormal lymph node morphology1 supporting datasetObp2bem1(IMPC)KmpchomozygoteLate adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Obp2bem1(IMPC)KmpcIndelmouse
Obp2btm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Obp2btm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Obp2btm44141(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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