Mcidas | multiciliate differentiation and DNA synthesis associated cell cycle protein

GeneMGI:3648807Synonyms: Gm6320, Mcin, +3 more

Physiological systems

17 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Growth/size/body region Hearing/vestibular/ear Nervous system Hematopoietic system Behavior/neurological

9 No significant impact

7 Not tested

Gene metrics:21Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased prepulse inhibition5 supporting datasetsMcidasem2(IMPC)TcphomozygoteEarly adult5.49x10-19 
increased circulating aspartate transaminase level1 supporting datasetMcidasem2(IMPC)TcphomozygoteEarly adult9.99x10-5 
increased grip strength1 supporting datasetMcidasem2(IMPC)TcphomozygoteEarly adult3.82x10-5 
male infertility1 supporting datasetMcidasem2(IMPC)TcphomozygoteEarly adultN/A * 
increased vertical activity1 supporting datasetMcidasem2(IMPC)TcphomozygoteEarly adult3.58x10-5 
female infertility1 supporting datasetMcidasem2(IMPC)TcphomozygoteEarly adultN/A * 
decreased lean body mass1 supporting datasetMcidasem2(IMPC)TcphomozygoteEarly adult2.21x10-5 
abnormal auditory brainstem response6 supporting datasetsMcidasem2(IMPC)TcphomozygoteEarly adult5.71x10-12 
increased circulating total protein level1 supporting datasetMcidasem2(IMPC)TcphomozygoteEarly adult4.03x10-6 
increased circulating alanine transaminase level1 supporting datasetMcidasem2(IMPC)TcphomozygoteEarly adult1.88x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mcidasem2(IMPC)TcpExon Deletionmouse

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