Spink6 | serine peptidase inhibitor, Kazal type 6

GeneMGI:3648654Synonyms: EG433180

Physiological systems

21 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Immune system Hematopoietic system

19 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased monocyte cell number	1 supporting dataset	Spink6^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.26x10^-5
increased Ly6C-positive mature NK cell number	1 supporting dataset	Spink6^{em1(IMPC)Ccpcz}	homozygote	Early adult	6.6x10^-5
decreased macrophage cell number	1 supporting dataset	Spink6^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.73x10^-8
decreased Ly6C-positive immature NK cell number	1 supporting dataset	Spink6^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.26x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Spink6.

Associated images

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Histopathology

There is no histopathology data found for Spink6.

IMPC related publications

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External links

No external links available for Spink6.

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*Spink6^{em1(IMPC)Ccpcz}*	Indel	‌	mouse
*Spink6^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Spink6^{tm88448(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes