Klhdc7b | kelch domain containing 7B

GeneMGI:3648212Synonyms: EG546648

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Nervous system Hearing/vestibular/ear Hematopoietic system Behavior/neurological

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



abnormal startle reflex	1 supporting dataset	Klhdc7b^em1(IMPC)H	homozygote	Late adult	5.77x10^-9
decreased prepulse inhibition	4 supporting datasets	Klhdc7b^em1(IMPC)H	homozygote	Early adult	1.19x10^-23
abnormal ear morphology	1 supporting dataset	Klhdc7b^em1(IMPC)H	homozygote	Early adult	7.13x10^-14
decreased startle reflex	1 supporting dataset	Klhdc7b^em1(IMPC)H	homozygote	Early adult	9.38x10^-5
abnormal auditory brainstem response	4 supporting datasets	Klhdc7b^em1(IMPC)H	homozygote	Early adult	1.23x10^-6
decreased lymphocyte cell number	1 supporting dataset	Klhdc7b^em1(IMPC)H	homozygote	Late adult	2.74x10^-8
increased eosinophil cell number	2 supporting datasets	Klhdc7b^em1(IMPC)H	homozygote	Late adult	2.89x10^-23
abnormal locomotor behavior	1 supporting dataset	Klhdc7b^em1(IMPC)H	homozygote	Late adult	2.83x10^-6
abnormal startle reflex	1 supporting dataset	Klhdc7b^em1(IMPC)H	homozygote	Early adult	7.68x10^-10

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Klhdc7b.

Associated images

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Histopathology

There is no histopathology data found for Klhdc7b.

IMPC related publications

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External links

No external links available for Klhdc7b.

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*Klhdc7b^em1(IMPC)H*	Exon Deletion	‌	mouse
*Klhdc7b^em2(IMPC)H*	Exon Deletion	‌	mouse

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