Tmem240 | transmembrane protein 240

GeneMGI:3648074Synonyms: Gm5151

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Liver/biliary system Behavior/neurological

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased grip strength	2 supporting datasets	Tmem240^{em1(IMPC)Ccpcz}	homozygote	Early adult	8.03x10^-6
hyperactivity	9 supporting datasets	Tmem240^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.06x10^-11
abnormal testis morphology	1 supporting dataset	Tmem240^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
tremors	1 supporting dataset	Tmem240^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.8x10^-5
increased exploration in new environment	1 supporting dataset	Tmem240^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.41x10^-7
increased circulating alkaline phosphatase level	1 supporting dataset	Tmem240^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.08x10^-8
increased fasting circulating glucose level	1 supporting dataset	Tmem240^{em1(IMPC)Ccpcz}	homozygote	Early adult	9.74x10^-5
decreased anxiety-related response	1 supporting dataset	Tmem240^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.04x10^-10
abnormal liver morphology	1 supporting dataset	Tmem240^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal locomotor behavior	1 supporting dataset	Tmem240^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.78x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmem240.

Associated images

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Histopathology

There is no histopathology data found for Tmem240.

IMPC related publications

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External links

No external links available for Tmem240.

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*Tmem240^{em1(IMPC)Ccpcz}*	Intra-exon deletion	‌	mouse
*Tmem240^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Tmem240^{tm437432(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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