Fam186b | family with sequence similarity 186, member B

GeneMGI:3647604Synonyms: EG545136

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

17 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes



increased circulating HDL cholesterol level	1 supporting dataset	Fam186b^{tm1b(KOMP)Mbp}	homozygote	Early adult	7.71x10^-5
increased fasting circulating glucose level	1 supporting dataset	Fam186b^{tm1b(KOMP)Mbp}	homozygote	Early adult	3.66x10^-5
increased circulating sodium level	1 supporting dataset	Fam186b^{tm1b(KOMP)Mbp}	homozygote	Early adult	1.2x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fam186b.

Associated images

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Histopathology

There is no histopathology data found for Fam186b.

IMPC related publications

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External links

No external links available for Fam186b.

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*Fam186b^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Fam186b^{tm1b(KOMP)Mbp}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Fam186b^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

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