Amt | aminomethyltransferase
Physiological systems
20 / 24 physiological systems tested
11 Significantly impacted by the knock-out
Embryo Growth/size/body region Digestive/alimentary Nervous system Vision/eye Limbs/digits/tail Hematopoietic system Skeleton Craniofacial Mortality/aging Cardiovascular system
9 No significant impact
4 Not tested
Data collections
Gene metrics:17Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| spina bifida | 1 supporting dataset | Amtem1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| abnormal retina blood vessel morphology | 1 supporting dataset | Amtem1(IMPC)Tcp | heterozygote | Early adult | 7.64x10-5 | ||
| increased erythrocyte cell number | 1 supporting dataset | Amtem1(IMPC)Tcp | heterozygote | Early adult | 1.26x10-5 | ||
| abnormal head shape | 1 supporting dataset | Amtem1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| microphthalmia | 1 supporting dataset | Amtem1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Amtem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| exencephaly | 1 supporting dataset | Amtem1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| anophthalmia | 1 supporting dataset | Amtem1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Amtem1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| cleft palate | 1 supporting dataset | Amtem1(IMPC)Tcp | homozygote | E15.5 | N/A * |
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External links
No external links available for Amt.
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| Amtem1(IMPC)Tcp | Exon Deletion | | mouse |
| Amttm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Amttm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |