Clrn2 | clarin 2

GeneMGI:3646230Synonyms: EG624224, mpc169H

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region Hearing/vestibular/ear Nervous system Behavior/neurological Skeleton

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased startle reflex	1 supporting dataset	Clrn2^em1(IMPC)J	homozygote	Early adult	3.74x10^-7
abnormal auditory brainstem response	5 supporting datasets	Clrn2^em1(IMPC)J	homozygote	Early adult	6.54x10^-13
decreased bone mineral content	2 supporting datasets	Clrn2^em1(IMPC)J	homozygote	Early adult	2.09x10^-9
abnormal startle reflex	1 supporting dataset	Clrn2^em1(IMPC)J	homozygote	Early adult	7.14x10^-8
decreased lean body mass	2 supporting datasets	Clrn2^em1(IMPC)J	homozygote	Early adult	5.63x10^-12
increased vertical activity	1 supporting dataset	Clrn2^em1(IMPC)J	homozygote	Early adult	9.56x10^-5
decreased prepulse inhibition	1 supporting dataset	Clrn2^em1(IMPC)J	homozygote	Early adult	5x10^-7
increased total body fat amount	2 supporting datasets	Clrn2^em1(IMPC)J	homozygote	Early adult	1.47x10^-11
decreased bone mineral density	1 supporting dataset	Clrn2^em1(IMPC)J	homozygote	Early adult	7.57x10^-10

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Clrn2.

Associated images

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Histopathology

There is no histopathology data found for Clrn2.

IMPC related publications

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External links

No external links available for Clrn2.

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*Clrn2^em1(IMPC)J*	Inter-exon deletion	‌	mouse
*Clrn2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

My Genes