Gm5148 | predicted gene 5148

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal spleen morphology1 supporting datasetGm5148em1(IMPC)CcpczhomozygoteEarly adultN/A * 
no spontaneous movement1 supporting datasetGm5148em1(IMPC)CcpczhomozygoteE18.5N/A * 
abnormal thymus morphology2 supporting datasetsGm5148em1(IMPC)CcpczheterozygoteEarly adultN/A * 
enlarged heart1 supporting datasetGm5148em1(IMPC)CcpczheterozygoteEarly adultN/A * 
abnormal heart morphology1 supporting datasetGm5148em1(IMPC)CcpczheterozygoteEarly adultN/A * 
enlarged thymus2 supporting datasetsGm5148em1(IMPC)CcpczheterozygoteEarly adultN/A * 
dilated aorta1 supporting datasetGm5148em1(IMPC)CcpczheterozygoteEarly adult1.76x10-5 
enlarged spleen1 supporting datasetGm5148em1(IMPC)CcpczheterozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetGm5148em1(IMPC)CcpczheterozygoteEarly adultN/A * 
abnormal testis morphology1 supporting datasetGm5148em1(IMPC)CcpczheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Gm5148em1(IMPC)CcpczWhole-gene deletionmouse
Gm5148tm232903(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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