Lipt1 | lipoyltransferase 1

GeneMGI:3645211Synonyms: EG623661

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Vision/eye Hematopoietic system Mortality/aging Cardiovascular system

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	3 supporting datasets	Lipt1^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Lipt1^em1(IMPC)Bay	heterozygote	Early adult	N/A ^*
abnormal retina blood vessel morphology	1 supporting dataset	Lipt1^em1(IMPC)Bay	heterozygote	Early adult	1.05x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lipt1.

Associated images

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Histopathology

There is no histopathology data found for Lipt1.

IMPC related publications

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External links

No external links available for Lipt1.

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*Lipt1^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Lipt1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Lipt1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Lipt1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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