Iigp1c | interferon inducible GTPase 1C

GeneMGI:3644953Synonyms: Gm4951

Physiological systems

22 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Growth/size/body region Behavior/neurological Cardiovascular system Renal/urinary system

17 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal kidney morphology1 supporting datasetIigp1cem1(IMPC)HmguhomozygoteLate adultN/A * 
increased grip strength2 supporting datasetsIigp1cem1(IMPC)HmguhomozygoteLate adult7.95x10-6 
abnormal startle reflex1 supporting datasetIigp1cem1(IMPC)HmguhomozygoteLate adult8.33x10-6 
abnormal gait1 supporting datasetIigp1cem1(IMPC)HmguhomozygoteLate adult3.32x10-5 
increased heart weight1 supporting datasetIigp1cem1(IMPC)HmguhomozygoteLate adult2.28x10-5 
abnormal lymph node morphology1 supporting datasetIigp1cem1(IMPC)HmguhomozygoteLate adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Iigp1cem1(IMPC)HmguExon Deletionmouse
Iigp1ctm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Iigp1ctm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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