Mylk4 | myosin light chain kinase family, member 4

GeneMGI:3643758Synonyms: EG238564

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Adipose tissue Growth/size/body region Vision/eye Skeleton

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased bone mineral content1 supporting datasetMylk4em1(IMPC)JhomozygoteEarly adult2.46x10-5 
decreased lean body mass2 supporting datasetsMylk4em1(IMPC)JhomozygoteEarly adult2.05x10-5 
increased total body fat amount1 supporting datasetMylk4em1(IMPC)JhomozygoteEarly adult7.92x10-5 
cataract1 supporting datasetMylk4em1(IMPC)JhomozygoteEarly adult9.45x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mylk4em1(IMPC)JExon Deletionmouse
Mylk4tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Mylk4tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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