Cep85l | centrosomal protein 85-like

GeneMGI:3642684Synonyms: Gm9766

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Immune system Integument Growth/size/body region Hearing/vestibular/ear Nervous system Behavior/neurological Renal/urinary system

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal auditory brainstem response	6 supporting datasets	Cep85l^em1(IMPC)Mbp	homozygote	Early adult	1.83x10^-6
abnormal startle reflex	1 supporting dataset	Cep85l^em1(IMPC)Mbp	homozygote	Early adult	1.14x10^-6
decreased prepulse inhibition	7 supporting datasets	Cep85l^em1(IMPC)Mbp	homozygote	Early adult	3.69x10^-52
abnormal skin morphology	1 supporting dataset	Cep85l^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Cep85l^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Cep85l^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal behavior	1 supporting dataset	Cep85l^em1(IMPC)Mbp	homozygote	Early adult	5.72x10^-5
decreased startle reflex	1 supporting dataset	Cep85l^em1(IMPC)Mbp	homozygote	Early adult	1.84x10^-5
abnormal lymph node morphology	1 supporting dataset	Cep85l^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged kidney	1 supporting dataset	Cep85l^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cep85l.

Associated images

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Histopathology

There is no histopathology data found for Cep85l.

IMPC related publications

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External links

No external links available for Cep85l.

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*Cep85l^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Cep85l^{tm1a(IMPC)Ccpcz}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	mouse
*Cep85l^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Cep85l^{tm1b(IMPC)Ccpcz}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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