Mir129-2 | microRNA 129-2

GeneMGI:3618711Synonyms: mmu-mir-129-2, Mirn129-2

Physiological systems

17 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Homeostasis/metabolism Pigmentation Integument Adipose tissue Growth/size/body region Limbs/digits/tail Behavior/neurological Skeleton Cardiovascular system

8 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased total body fat amount2 supporting datasetsMir129-2em1(IMPC)KmpchomozygoteLate adult8.51x10-10 
abnormal coat/hair pigmentation2 supporting datasetsMir129-2em1(IMPC)KmpchomozygoteLate adult6.78x10-5 
short tibia2 supporting datasetsMir129-2em1(IMPC)KmpchomozygoteEarly adult3.38x10-5 
abnormal vertebral arch morphology1 supporting datasetMir129-2em1(IMPC)KmpchomozygoteLate adult2.03x10-5 
increased heart weight1 supporting datasetMir129-2em1(IMPC)KmpchomozygoteLate adult2.42x10-5 
decreased grip strength2 supporting datasetsMir129-2em1(IMPC)KmpchomozygoteLate adult3.35x10-8 
abnormal spine curvature1 supporting datasetMir129-2em1(IMPC)KmpchomozygoteLate adult7.3x10-6 
decreased lean body mass2 supporting datasetsMir129-2em1(IMPC)KmpchomozygoteLate adult2.19x10-10 
decreased bone mineral content1 supporting datasetMir129-2em1(IMPC)KmpchomozygoteEarly adult1.78x10-6 
short tibia1 supporting datasetMir129-2em1(IMPC)KmpchomozygoteLate adult4.01x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mir129-2em1(IMPC)KmpcDeletionmouse
Mir129-2tm1(mirKO)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell

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