Cpa2 | carboxypeptidase A2, pancreatic

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Vision/eye

15 No significant impact

6 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:70Adult tissues
0Embryo tissues

Phenotypes

decreased circulating chloride level1 supporting datasetCpa2tm1b(EUCOMM)HmguhomozygoteEarly adult1.13x10-6 
female infertility1 supporting datasetCpa2tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
abnormal lens morphology1 supporting datasetCpa2tm1b(EUCOMM)HmguhomozygoteEarly adult4.07x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cpa2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Cpa2tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Cpa2tm43294(L1L2_st2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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