Ccdc8 | coiled-coil domain containing 8

GeneMGI:3612184Synonyms: ENSMUSG00000041117

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Adipose tissue Mortality/aging

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	3 supporting datasets	Ccdc8^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
increased total body fat amount	1 supporting dataset	Ccdc8^em1(IMPC)Tcp	heterozygote	Early adult	7.36x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ccdc8.

Associated images

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Histopathology

There is no histopathology data found for Ccdc8.

IMPC related publications

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External links

No external links available for Ccdc8.

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*Ccdc8^em1(IMPC)Tcp*	Intra-exon deletion	‌	mouse
*Ccdc8^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ccdc8^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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