Fam167a | family with sequence similarity 167, member A

Physiological systems

22 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Liver/biliary system Respiratory system Hematopoietic system Cardiovascular system

13 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal coat/ hair morphology	2 supporting datasets	Fam167a^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.34x10^-7
increased lung tissue damping	1 supporting dataset	Fam167a^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.88x10^-6
enlarged spleen	1 supporting dataset	Fam167a^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Fam167a^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Fam167a^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal heart morphology	2 supporting datasets	Fam167a^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Fam167a^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal coat appearance	1 supporting dataset	Fam167a^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.71x10^-8
enlarged heart	2 supporting datasets	Fam167a^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Fam167a^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fam167a.

Associated images

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Histopathology

There is no histopathology data found for Fam167a.

IMPC related publications

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External links

No external links available for Fam167a.

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*Fam167a^{em1(IMPC)Ccpcz}*	Intra-exon deletion	‌	mouse
*Fam167a^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Fam167a^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Fam167a^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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