Fam167a | family with sequence similarity 167, member A

Physiological systems

22 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Liver/biliary system Respiratory system Hematopoietic system Cardiovascular system

13 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:13Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal coat/ hair morphology2 supporting datasetsFam167aem1(IMPC)CcpczhomozygoteEarly adult1.34x10-7 
increased lung tissue damping1 supporting datasetFam167aem1(IMPC)CcpczhomozygoteEarly adult5.88x10-6 
enlarged spleen1 supporting datasetFam167aem1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetFam167aem1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged thymus1 supporting datasetFam167aem1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal heart morphology2 supporting datasetsFam167aem1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal thymus morphology1 supporting datasetFam167aem1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal coat appearance1 supporting datasetFam167aem1(IMPC)CcpczhomozygoteEarly adult1.71x10-8 
enlarged heart2 supporting datasetsFam167aem1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal testis morphology1 supporting datasetFam167aem1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* Does not have a P-value assigned because it was manually marked as significant.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fam167aem1(IMPC)CcpczIntra-exon deletionmouse
Fam167atm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Fam167atm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Fam167atm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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