Il20ra | interleukin 20 receptor, alpha

Physiological systems

21 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system

19 No significant impact

3 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

increased red blood cell distribution width1 supporting datasetIl20ratm1.1(KOMP)VlcghomozygoteEarly adult1.62x10-6 
increased circulating alanine transaminase level1 supporting datasetIl20ratm1.1(KOMP)VlcghomozygoteEarly adult9.24x10-8 
increased circulating aspartate transaminase level1 supporting datasetIl20ratm1.1(KOMP)VlcghomozygoteEarly adult1.8x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Il20ratm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Il20ratm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Il20ratm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Il20ratm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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