Pramel17 | PRAME like 17

GeneMGI:3588238Synonyms: B020004J07Rik

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Growth/size/body region Limbs/digits/tail Hearing/vestibular/ear Cardiovascular system Renal/urinary system

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal tail morphology	1 supporting dataset	Pramel17^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.27x10^-6
increased kidney weight	1 supporting dataset	Pramel17^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.17x10^-5
enlarged heart	1 supporting dataset	Pramel17^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal auditory brainstem response	1 supporting dataset	Pramel17^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.42x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pramel17.

Associated images

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Histopathology

There is no histopathology data found for Pramel17.

IMPC related publications

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External links

No external links available for Pramel17.

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*Pramel17^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Pramel17^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Pramel17^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Pramel17^{tm43374(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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