Rnf223 | ring finger 223

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Immune system Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Cardiovascular system Renal/urinary system

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal retina morphology	1 supporting dataset	Rnf223^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.03x10^-6
abnormal lymph node morphology	1 supporting dataset	Rnf223^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Rnf223^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Rnf223^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Rnf223^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Rnf223^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Rnf223^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Rnf223^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Rnf223^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
single kidney	1 supporting dataset	Rnf223^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* Does not have a P-value assigned because it was manually marked as significant.

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lacZ Expression

No adult expression data available for Rnf223.

Associated images

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Histopathology

There is no histopathology data found for Rnf223.

IMPC related publications

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External links

No external links available for Rnf223.

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*Rnf223^{em1(IMPC)Ccpcz}*	Intra-exon deletion	‌	mouse

My Genes