Rnf223 | ring finger 223

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Immune system Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Cardiovascular system Renal/urinary system

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal retina morphology1 supporting datasetRnf223em1(IMPC)CcpczhomozygoteEarly adult2.03x10-6 
abnormal lymph node morphology1 supporting datasetRnf223em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged heart1 supporting datasetRnf223em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal heart morphology1 supporting datasetRnf223em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged thymus1 supporting datasetRnf223em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal thymus morphology1 supporting datasetRnf223em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged lymph nodes1 supporting datasetRnf223em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetRnf223em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetRnf223em1(IMPC)CcpczhomozygoteEarly adultN/A * 
single kidney1 supporting datasetRnf223em1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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