Cdkl4 | cyclin dependent kinase like 4

GeneMGI:3587025Synonyms: LOC381113

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

25Embryo tissues

Phenotypes

Phy. System:



cataract	1 supporting dataset	Cdkl4^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	3.61x10^-5
increased circulating alkaline phosphatase level	1 supporting dataset	Cdkl4^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.15x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cdkl4.

Associated images

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Histopathology

There is no histopathology data found for Cdkl4.

IMPC related publications

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External links

No external links available for Cdkl4.

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*Cdkl4^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Cdkl4^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Cdkl4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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