Fbxw20 | F-box and WD-40 domain protein 20

Physiological systems

22 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Immune system Endocrine/exocrine gland Integument Growth/size/body region Digestive/alimentary Hematopoietic system Skeleton Craniofacial

14 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged spleen1 supporting datasetFbxw20em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal tooth morphology2 supporting datasetsFbxw20em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged stomach2 supporting datasetsFbxw20em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal spleen morphology2 supporting datasetsFbxw20em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetFbxw20em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged thymus1 supporting datasetFbxw20em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal stomach morphology2 supporting datasetsFbxw20em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged lymph nodes1 supporting datasetFbxw20em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal lymph node morphology1 supporting datasetFbxw20em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal thymus morphology1 supporting datasetFbxw20em1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fbxw20em1(IMPC)CcpczExon Deletionmouse

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