Mfsd2b | MFSD2 lysolipid transporter B, sphingolipid

GeneMGI:3583946Synonyms: Gm1964, major facilitator superfamily domain containing 2B

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Growth/size/body region Hematopoietic system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating iron level	1 supporting dataset	Mfsd2b^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.27x10^-7
decreased erythrocyte cell number	1 supporting dataset	Mfsd2b^{tm1a(KOMP)Wtsi}	homozygote	Early adult	3.46x10^-5
increased mean corpuscular hemoglobin	1 supporting dataset	Mfsd2b^{tm1a(KOMP)Wtsi}	homozygote	Early adult	4.7x10^-5
increased body length	1 supporting dataset	Mfsd2b^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.2x10^-5
abnormal vibrissa morphology	1 supporting dataset	Mfsd2b^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.57x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mfsd2b.

Associated images

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Histopathology

There is no histopathology data found for Mfsd2b.

IMPC related publications

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External links

No external links available for Mfsd2b.

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*Mfsd2b^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Mfsd2b^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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