Grxcr1 | glutaredoxin, cysteine rich 1

GeneMGI:3577767Synonyms: pi, tde

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Nervous system Hearing/vestibular/ear Behavior/neurological

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal ear morphology	1 supporting dataset	Grxcr1^em1(IMPC)J	homozygote	Early adult	6.18x10^-5
abnormal auditory brainstem response	5 supporting datasets	Grxcr1^em1(IMPC)J	homozygote	Early adult	6.54x10^-13
increased circulating cholesterol level	1 supporting dataset	Grxcr1^em1(IMPC)J	homozygote	Early adult	5.05x10^-5
decreased prepulse inhibition	2 supporting datasets	Grxcr1^em1(IMPC)J	homozygote	Early adult	1.61x10^-17
abnormal startle reflex	1 supporting dataset	Grxcr1^em1(IMPC)J	homozygote	Early adult	5.82x10^-6
hyperactivity	2 supporting datasets	Grxcr1^em1(IMPC)J	homozygote	Early adult	4.95x10^-7
decreased startle reflex	1 supporting dataset	Grxcr1^em1(IMPC)J	homozygote	Early adult	9.89x10^-7
head bobbing	1 supporting dataset	Grxcr1^em1(IMPC)J	homozygote	Early adult	5.88x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Grxcr1.

Associated images

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Histopathology

There is no histopathology data found for Grxcr1.

IMPC related publications

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External links

No external links available for Grxcr1.

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*Grxcr1^em1(IMPC)J*	Intra-exon deletion	‌	mouse
*Grxcr1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Grxcr1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Grxcr1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Grxcr1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Grxcr1^{tm3a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Grxcr1^{tm466383(Ifitm2_intron_L1L2_GT1_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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