Eme1 | essential meiotic structure-specific endonuclease 1

GeneMGI:3576783

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Immune system Hematopoietic system

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased hematocrit	1 supporting dataset	Eme1^{tm1.1(KOMP)Wtsi}	homozygote	Early adult	2.9x10^-5
increased erythrocyte cell number	1 supporting dataset	Eme1^{tm1.1(KOMP)Wtsi}	homozygote	Early adult	1.82x10^-6
abnormal spleen morphology	1 supporting dataset	Eme1^{tm1.1(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Eme1.

Associated images

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Histopathology

There is no histopathology data found for Eme1.

IMPC related publications

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External links

No external links available for Eme1.

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*Eme1^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell mouse
*Eme1^{tm1.1(KOMP)Wtsi}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Eme1^{tm431825(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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