Pram1 | PML-RAR alpha-regulated adaptor molecule 1

GeneMGI:3576625

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Growth/size/body region Cardiovascular system

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



increased heart weight	1 supporting dataset		Pram1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult		3.04x10^-11

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pram1.

Associated images

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Histopathology

There is no histopathology data found for Pram1.

IMPC related publications

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External links

No external links available for Pram1.

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*Pram1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Pram1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Pram1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Pram1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Pram1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Pram1^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Pram1^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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