Pskh1 | protein serine kinase H1

GeneMGI:3528383Synonyms: E130013P03Rik, b2b1230Clo

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Cardiovascular system Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

1Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



improved glucose tolerance	1 supporting dataset	Pskh1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.54x10^-5
increased fasting circulating glucose level	1 supporting dataset	Pskh1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.59x10^-7
hemorrhage	1 supporting dataset	Pskh1^{tm1b(EUCOMM)Wtsi}	homozygote	E15.5	N/A ^*
increased heart weight	1 supporting dataset	Pskh1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.21x10^-7
preweaning lethality, complete penetrance	1 supporting dataset	Pskh1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
edema	1 supporting dataset	Pskh1^{tm1b(EUCOMM)Wtsi}	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pskh1.

Associated images

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Histopathology

There is no histopathology data found for Pskh1.

IMPC related publications

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External links

No external links available for Pskh1.

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*Pskh1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Pskh1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Pskh1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Pskh1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Pskh1^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pskh1^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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