Trpa1 | transient receptor potential cation channel, subfamily A, member 1

GeneMGI:3522699Synonyms: ANKTM1

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Adipose tissue Growth/size/body region Vision/eye Behavior/neurological

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal vocalization1 supporting datasetTrpa1em1(IMPC)JhomozygoteEarly adult1.04x10-6 
increased total body fat amount1 supporting datasetTrpa1em1(IMPC)JhomozygoteEarly adult1.4x10-5 
abnormal cornea morphology1 supporting datasetTrpa1em1(IMPC)JhomozygoteEarly adult2.79x10-5 
decreased lean body mass1 supporting datasetTrpa1em1(IMPC)JhomozygoteEarly adult1.18x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Trpa1em1(IMPC)JExon Deletionmouse
Trpa1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Trpa1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Trpa1tm2(EGFP_CreERT2)WtsiReporter-tagged deletion allele (with selection cassette)ES Cell

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