Fbxw15 | F-box and WD-40 domain protein 15

GeneMGI:3505701Synonyms: Fbxo12J

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Respiratory system Skeleton Craniofacial Renal/urinary system

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating phosphate level1 supporting datasetFbxw15em1(IMPC)CcpczhomozygoteEarly adult5.57x10-6 
single kidney1 supporting datasetFbxw15em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal zygomatic bone morphology1 supporting datasetFbxw15em1(IMPC)CcpczhomozygoteEarly adult8.12x10-5 
abnormal lung morphology1 supporting datasetFbxw15em1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fbxw15em1(IMPC)CcpczExon Deletionmouse

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