Fbxw10 | F-box and WD-40 domain protein 10

GeneMGI:3052463Synonyms: SM2SH2, Fbw10, +1 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Adipose tissue Growth/size/body region Renal/urinary system

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged lymph nodes	1 supporting dataset	Fbxw10^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
enlarged urinary bladder	1 supporting dataset	Fbxw10^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
decreased total body fat amount	1 supporting dataset	Fbxw10^em1(IMPC)Tcp	homozygote	Early adult	7.37x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fbxw10.

Associated images

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Histopathology

There is no histopathology data found for Fbxw10.

IMPC related publications

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External links

No external links available for Fbxw10.

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*Fbxw10^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Fbxw10^{tm1(NCOM)Cmhd}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Fbxw10^{tm305(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes