Rtl5 | retrotransposon Gag like 5

GeneMGI:3045324Synonyms: Mar5, 6430402L03Rik, +2 more

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Growth/size/body region Vision/eye Behavior/neurological Cardiovascular system Renal/urinary system

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

microphthalmia1 supporting datasetRtl5em1(IMPC)MbphemizygoteEarly adultN/A * 
increased freezing behavior1 supporting datasetRtl5em1(IMPC)MbphemizygoteEarly adult7.07x10-7 
abnormal eye morphology1 supporting datasetRtl5em1(IMPC)MbphemizygoteEarly adultN/A * 
enlarged heart1 supporting datasetRtl5em1(IMPC)MbphemizygoteEarly adultN/A * 
abnormal heart morphology1 supporting datasetRtl5em1(IMPC)MbphemizygoteEarly adultN/A * 
enlarged kidney1 supporting datasetRtl5em1(IMPC)MbphemizygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetRtl5em1(IMPC)MbphemizygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rtl5em1(IMPC)MbpExon Deletionmouse
Rtl5tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Rtl5tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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