Mamld1 | mastermind-like domain containing 1

GeneMGI:3045303Synonyms: G630014P10Rik

Physiological systems

17 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Limbs/digits/tail Hematopoietic system Skeleton

10 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal cholesterol homeostasis	1 supporting dataset	Mamld1^{tm1.1(NCOM)Mfgc}	hemizygote	Early adult	1.14x10^-6
short tibia	1 supporting dataset	Mamld1^{tm1.1(NCOM)Mfgc}	hemizygote	Early adult	5.2x10^-7
increased leukocyte cell number	1 supporting dataset	Mamld1^{tm1.1(NCOM)Mfgc}	hemizygote	Early adult	4.56x10^-6
decreased body length	1 supporting dataset	Mamld1^{tm1.1(NCOM)Mfgc}	homozygote	Early adult	9.94x10^-5
decreased respiratory quotient	1 supporting dataset	Mamld1^{tm1.1(NCOM)Mfgc}	hemizygote	Early adult	4.47x10^-7
increased lymphocyte cell number	1 supporting dataset	Mamld1^{tm1.1(NCOM)Mfgc}	hemizygote	Early adult	4.14x10^-6
decreased bone mineral content	2 supporting datasets	Mamld1^{tm1.1(NCOM)Mfgc}	homozygote	Early adult	5.78x10^-10
decreased lean body mass	1 supporting dataset	Mamld1^{tm1.1(NCOM)Mfgc}	homozygote	Early adult	1.18x10^-7
short tibia	1 supporting dataset	Mamld1^{tm1.1(NCOM)Mfgc}	homozygote	Early adult	1.22x10^-6
increased total body fat amount	1 supporting dataset	Mamld1^{tm1.1(NCOM)Mfgc}	homozygote	Early adult	3.95x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mamld1.

Associated images

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Histopathology

There is no histopathology data found for Mamld1.

IMPC related publications

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External links

No external links available for Mamld1.

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*Mamld1^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell mouse
*Mamld1^{tm1.1(NCOM)Mfgc}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

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